All of Erie High School's Career and Technical Education programs provide articulation agreements with local and statewide colleges and universities, guaranteeing students postsecondary credit for their CTE program. Students in the Medical Assistant program benefit from articulation agreements with the following institutions:
- Commonwealth Technical Institute, 9 credits aligned to Medical Office Assistant Associate in Specialized Business (ASB) program
- Delaware County Community College, 9 credits aligned to Medical Assistant, Associate of Applied Science (AAS) Degree program
- Great Lakes Institute of Technology, Advanced Placement Credit
- Institute of Medical & Business Careers, curricular articulation agreement
- Laurel Technical Institute, Advanced Placement Agreement